RxCalc
Introduction During my time as a provisionally registered pharmacist rotating through Therapeutic Drug Monitoring (TDM), I realized that pharmacokinetic calculations were highly repetitive tasks. While pharmacokinetic modeling is useful, clinical decisions to withhold or adjust narrow therapeutic index drugs ultimately rely on the patient's clinical response. For instance, we monitor CRP, temperature, and white blood cell count for vancomycin and gentamicin, while actively tracking creatinine clearance changes for signs of toxicity. Mathematically, simply looking at a measured drug level often allows us to easily decide whether to withhold, adjust, or continue the current dose. This frequently renders subsequent pharmacokinetic calculations redundant. Consequently, I concluded that these calculations are primarily beneficial for dosage adjustments in toxicity cases. To streamline this process, I created an Excel-based TDM calculator in Excel sheet and OpenAsApp Link . The spreadsh...