Posts

Showing posts with the label 5alpha-reductase inhibitor

Benign Prostatic Hyperplasia

Image
Introduction Benign Prostatic Hyperplasia (BPH) is a histologic condition of proliferation of smooth muscle and epithelial cells in prostatic transition zone. The prevalence increases with age , affecting approximately 42% of men between the ages of 51 and 60 years and 82% of men between the ages of 71 and 80 years. BPH may progresses to benign prostatic enlargement (BPE) and subsequent bladder outlet obstruction (BOO), leading to lower urinary tract symptoms (LUTS). Lower tract urinary symptoms (LUTS) may include Storage symptoms : daytime frequency, urgency, nocturia and incontinence Voiding symptoms: weak stream, dribbling, dysuria, straining Symptoms can significantly impact quality of life. Complications include acute urinary retention, urinary tract infection, bladder calculi and renal insufficiency. Treatment Principles The severity of reported BPH symptoms guides selection of treatment. Validated severity and bother scores exist, such as the American Urological Association Sym...