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Aseptic Technique

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Introduction Aseptic technique is a skill in the compounding of sterile preparations that is independent of equipment [e.g. primary engineering control (PEC) and secondary engineering controls (i.e. cleanroom) ] and environment. Proper use of Laminar Airflow Workbench (LAFW) An LAFW should operate continuously when in use. Before use, all interior working surfaces of the LAFW must be cleaned from the cleanest part of the LAFW to dirtiest part with sterile 70% isopropyl alcohol (IPA) or another disinfecting agent and a clean, nonshedding, lint-free wipe. The LAFW should be cleaned and disinfected frequently, including at the beginning of the wok shift, before the start of each batch, every 30 minutes during continuous compounding periods, when there are spills, and when there is known or suspected contamination from a lapse in the aseptic technique process. Nothing should touch the HEPA filter. Nothing should disrupt or block the unidirectional airflow between the high-efficiency pa...