Rx Note

Introduction A unit-dose medication distribution system uses medications packaged in unit-dose or single-unit packages. A single-unit package contains one dosage form of medication (e.g., one capsule, one 5 ml volume of liquid, etc.). A unit-dose package contains the dose of a medication ordered for a patient (e.g. two 250 mg tablets for a 500 mg dose). However, not all medications are available from the manufacturer in single-unit or unit-dose packages. Hence, pharmacies sometimes have to purchase medications in bulk containers and repackage them in unit-dose or single-unit packages. Important Elements Department's policy and procedures for repackaging should clearly outlines the following elements. Space or facility requirements Clean with adequate lighting and ventilation, as well as temperature and humidity controls Food and beverages must not be allowed in the repackaging area. Labelling format Generic name of medication Name of manufacturer or distributor Dosage form, inc...

Introduction Recently, you are assigned the task of updating extemporaneous preparation formulae at your hospital. Much to your surprise, a significant number of extemporaneous preparations originated in The Pharmaceutical Codex 1994 (or 1973). Although you managed to identify the extemporaneous preparation formulae, no stability data was provided. Today, stability information can be obtained from manufacturer’s labelling information (such as in the package insert), the USP compounding monographs, or peer-reviewed articles and references , such as articles in American Journal of Health-System Pharmacy, the International Journal of Pharmaceutical Compounding. However, what should you recommend if stability data is unavailable? USP General Chapter <795> and <797> The revision of <795> and <797>, published in November 2022, became official on 1 November 2023, replacing the previous revision of <795> from 2014 and <797> from 2008. In general, the use ...