Chronic Obstructive Pulmonary Disease
Introduction Chronic Obstructive Pulmonary Disease (COPD) is a heterogenous lung condition characterized by chronic respiratory symptoms (dyspnoea, cough , sputum production and/or exacerbations) due to abnormalities of the airways (bronchitis, bronchiolitis) and/or alveoli (emphysema) that cause persistent, often progressive, airflow obstruction. The main environmental exposures leading to COPD are tobacco smoking and the inhalation of toxic particles and gases from household and outdoor air pollution, but other environmental and host factors (including genetic factors, abnormal lung development and accelerated lung aging) can also contribute. Forced spirometry that demonstrates the presence of a non-fully reversible airflow obstruction (i.e. FEV1/FVC <0.7 post-bronchodilator) is mandatory to establish the diagnosis of COPD. Management Apart from smoking cessation and vaccination (e.g. COVID-19 , influenza, pneumococcal, RSV and dTaP vaccines, and zoster vaccine to protect agains...