Rx Note

Introduction Ferric ammonium citrate 400 mg/5 ml mixture (FAC syrup) is a commonly prescribed medication for prevention and treatment of iron-deficiency anaemia in premature infants at Malaysia. FAC mixture is commonly supplied for 3-4 months post discharge or until next review. Extemporaneous Formulation (BPC 1973, page 742) Ferric ammonium citrate BP 80 g Compound orange spirit BP 2 ml Syrup BP 1 00 ml Double strength chloroform water BP 500 ml Water q.s. to 1000 ml. * This product would be recently prepared as double strength chloroform water BP acts as a preservative and therefore would attract a four-week discard date. * The dose should be taken well diluted with water. Dosage Calculation Dosing of FAC syrup is based on elemental iron needed per day. As per Frank Shann Drug Doses, 2017 , ferrous salts dosage is as below: Prophylaxis, 2 mg/kg/day elemental iron oral Treatment, 6 mg/kg/day elemental iron oral. * In real practice, the dosing prescribed can be within the range of 2-...

Introduction In life, there are certain facts that are beyond the scope of our understanding, but are important to remember. For example, calcium lactate 1200 mg provides less elemental calcium than calcium carbonate 500 mg. Elemental Calcium Content Elemental calcium content in Calcium acetate 667 mg tablet 169 mg elemental calcium (25%) Calcium citrate 1500 mg tablet 315 mg elemental calcium (21%) Calcium carbonate 500 mg tablet 200 mg elemental calcium (40%) Calcium lactate 300 mg tablet 39 mg elemental calcium (13%) NOTE: Calcium absorption from calcium acetate formulation is poor, hence it is used as phosphate binder, but not for calcium replacement. Calcium carbonate has acid-dependent absorption and should be taken with meals. Most people tolerate calcium carbonate well, but some people complain of mild constipation or feeling bloated. Calcium citrate are absorbed more easily than calcium carbonate. It has acid-independent absorption and can be...