Warfarin
Introduction Warfarin is an oral anticoagulant - a medicine that increases the time it takes for your blood to clot. It helps to stop unwanted clots from forming inside blood vessels. However, it does not dissolve clots, but prevents them from growing larger, allowing the body's natural system to break down the clot over time. A thrombosis can cause a stroke, a heart attack, a deep vein thrombosis or a pulmonary embolism. However, warfarin use can be challenging in clinical settings due to Its narrow therapeutic range The influence of various factors on dosing such as genetic variation, drug interactions and diet. The time spent outside the therapeutic range increases the risk of bleeding and/or thromboembolic complications that warfarin is intended to prevent. Baseline Testing Before initiating warfarin therapy, certain baseline tests should be obtained Baseline prothrombin time (PT) with international normalized ratio (INR) and baseline activated partial thromboplastin time (aPT...