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Showing posts with the label Memantine

Dementia

Introduction Dementia is a life-limiting, progressive syndrome characterized by cognitive and functional decline . The common causes of dementia are Alzheimer disease (50 to 75% of cases) , vascular dementia (20 to 30%), frontotemporal dementias (up to 10%), and dementia with Lewy bodies and Parkinson disease dementia (up to 10%). Many patients have more than one subtype of dementia (mixed dementia); the most common combination is Alzheimer disease and vascular dementia. Risk Factors Increasing age is the most significant risk factor. The " Dementia prevention, intervention, and care: 2020 report of the Lancet Commission " identified 12 potentially modifiable risk factors for dementia - addressing these factors may prevent or delay dementia. Air pollution (including second-hand smoke exposure) Hazardous alcohol consumption Depression Diabetes Poor education Head injury Hypertension Obesity Physical inactivity Smoking Social isolation Behavioural and Psychological Symptoms o...