Rx Note

Introduction When I was a provisional registered pharmacist, I used to confuse tranexamic acid as a NSAID (cause it sounds similar to mefenamic acid). On the other hand, it is a medication used to treat or prevent excessive blood loss from major trauma, postpartum bleeding, surgery, tooth removal, nosebleeds and heavy menstruation . Menorrhagia Menorrhagia is excessive (heavy) menstrual blood loss (i.e. blood loss of 60-80 ml or more period, compared with average loss of 30-40 ml), which occurs over several consecutive cycles. Oral tranexamic acid reduces the volume of menstrual blood loss by about half through its antifibrinolytic effect, which increases blood clotting. Dosage varies, according to the heaviness and duration of bleeding: 1 to 1.5 g 3 or 4 times daily for the first 3-5 days of each cycle. Although tranexamic acid is available as an OTC medication in oversea, it is a prescription medication at Malaysia ( Group B poison ). 5% Mouthwash Tranexamic acid can be extemporan...

Introduction Menorrhagia is excessive (heavy) menstrual blood loss (i.e. blood loss of 60-80 ml or more period, compared with average loss of 30-40 ml), which occurs over several consecutive cycles. NOTE: A period normally lasts 2-7 days, with the average period being 5 days long. Medicine-Induced Menstrual Bleeding Occasionally, medicines can change menstrual bleeding patterns. Anticoagulants Monoamine oxidase inhibitors Phenothiazines Steroids Tamoxifen Thyroid hormones Management Oral tranexamic acid reduces the volume of menstrual blood loss by about 50% through its antifibrinolytic effect , which increases blood clotting. It provides symptomatic relief but does not resolve underlying causes. Dosage varies, according to the heaviness and duration of bleeding: 1 to 1.5 g 3 or 4 times daily for the first 3-5 days of each cycle. Although tranexamic acid is available as an OTC medication in oversea, it is a prescription medication at Malaysia ( Group B poison ). The use of NSAID (...